Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
16756440
TITLE
A genetically informed study of the processes underlying the association between parental marital instability and offspring adjustment.
ABSTRACT
Parental divorce is associated with problematic offspring adjustment, but the relation may be due to shared genetic or environmental factors. One way to test for these confounds is to study offspring of twins discordant for divorce. The current analyses used this design to separate the mechanisms responsible for the association between parental divorce, experienced either before or after the age of 16, and offspring well-being. The results were consistent with a causal role of divorce in earlier initiation of sexual intercourse and emotional difficulties, in addition to a greater probability of educational problems, depressed mood, and suicidal ideation. In contrast, the increased risk for cohabitation and earlier initiation of drug use was explained by selection factors, including genetic confounds. ((c) 2006 APA, all rights reserved).
DATE PUBLISHED
2006 May
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2006/06/08 09:00
medline 2006/11/10 09:00
entrez 2006/06/08 09:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
D'Onofrio BM D'Onofrio Brian M BM Department of Psychology, University of Virginia, VA 47405, USA. bmdonofr@indiana.edu
Turkheimer E Turkheimer Eric E
Emery RE Emery Robert E RE
Slutske WS Slutske Wendy S WS
Heath AC Heath Andrew C AC
Madden PA Madden Pamela A PA
Martin NG Martin Nicholas G NG
INVESTIGATORS
JOURNAL
VOLUME: 42
ISSUE: 3
TITLE: Developmental psychology
ISOABBREVIATION: Dev Psychol
YEAR: 2006
MONTH: May
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0012-1649
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Dev Psychol
COUNTRY: United States
ISSNLINKING: 0012-1649
NLMUNIQUEID: 0260564
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
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GRANTS
GRANTID AGENCY COUNTRY
AA000264 NIAAA NIH HHS United States
AA07535 NIAAA NIH HHS United States
MH67300 NIMH NIH HHS United States
R01 HD056354 NICHD NIH HHS United States
R01 HD056354-01 NICHD NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adult
Alcoholic Intoxication epidemiology
Child epidemiology
Child Behavior Disorders genetics
Divorce genetics
Educational Status genetics
Female genetics
Humans genetics
Longitudinal Studies genetics
Male genetics
Marijuana Abuse epidemiology
Marital Status epidemiology
Marriage psychology
Parent-Child Relations psychology
Sexual Behavior psychology
Social Adjustment psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's
OTHERID SOURCE
NIHMS243218 NLM
PMC2965635 NLM
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