Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
16710775
TITLE
Assortative mating for cigarette smoking and for alcohol consumption in female Australian twins and their spouses.
ABSTRACT
BACKGROUND NlmCategory: BACKGROUND
Non-random mating affects population variation for substance use and dependence. Developmentally, mate selection leading to positive spousal correlations for genetic similarity may result in increased risk for substance use and misuse in offspring. Mate selection varies by cohort and thus, assortative mating in one generation may produce marked changes in rates of substance use in the next. We aim to clarify the mechanisms contributing to spousal similarity for cigarette smoking and alcohol consumption.
METHODS NlmCategory: METHODS
Using data from female twins and their male spouses, we fit univariate and bivariate twin models to examine the contribution of primary assortative mating and reciprocal marital interaction to spousal resemblance for regular cigarette smoking and nicotine dependence, and for regular alcohol use and alcohol dependence.
RESULTS NlmCategory: RESULTS
We found that assortative mating significantly influenced regular smoking, regular alcohol use, nicotine dependence and alcohol dependence. The bivariate models for cigarette smoking and alcohol consumption also highlighted the importance of primary assortative mating on all stages of cigarette smoking and alcohol consumption, with additional evidence for assortative mating across the two stages of alcohol consumption.
CONCLUSIONS NlmCategory: CONCLUSIONS
Women who regularly used, and subsequently were dependent on cigarettes or alcohol were more likely to marry men with similar behaviors. After mate selection had occurred, one partner's cigarette or alcohol involvement did not significantly modify the other partner's involvement with these psychoactive substances.
DATE PUBLISHED
2006 Jul
HISTORY
PUBSTATUS PUBSTATUSDATE
received 2005/12/19
accepted 2006/03/02
aheadofprint 2006/05/19
pubmed 2006/05/20 09:00
medline 2006/09/16 09:00
entrez 2006/05/20 09:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Agrawal A Agrawal Arpana A Department of Psychiatry, Washington University School of Medicine, 660 S. Euclid, 8134, St. Louis, MO 63110, USA. arpana@matlock.wustl.edu
Heath AC Heath Andrew C AC
Grant JD Grant Julia D JD
Pergadia ML Pergadia Michele L ML
Statham DJ Statham Dixie J DJ
Bucholz KK Bucholz Kathleen K KK
Martin NG Martin Nicholas G NG
Madden PA Madden Pamela A F PA
INVESTIGATORS
JOURNAL
VOLUME: 36
ISSUE: 4
TITLE: Behavior genetics
ISOABBREVIATION: Behav. Genet.
YEAR: 2006
MONTH: Jul
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-8244
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Behav Genet
COUNTRY: United States
ISSNLINKING: 0001-8244
NLMUNIQUEID: 0251711
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Twin Study
COMMENTS AND CORRECTIONS
REFTYPE REFSOURCE REFPMID NOTE
ErratumIn Behav Genet. 2006 Nov;36(6):996
GRANTS
GRANTID AGENCY COUNTRY
AA07535 NIAAA NIH HHS United States
AA07728 NIAAA NIH HHS United States
AA10248 NIAAA NIH HHS United States
AA11998 NIAAA NIH HHS United States
AA13221 NIAAA NIH HHS United States
DA12854 NIDA NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Alcohol Drinking psychology
Australia psychology
Choice Behavior psychology
Environment psychology
Female psychology
Humans psychology
Male psychology
Smoking psychology
Spouses psychology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's