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|
| PMID |
|
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| TITLE |
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| Hypotheses on the effect of cadmium on glutathione content of red blood corpuscles. |
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| ABSTRACT |
|
|
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| Previous studies have shown that Glutathione, a tripeptide found in blood, is involved in protecting against toxins. Glutathione levels are known to drop in response to cadmium. Using 15 twin pairs, we modeled the effect of cadmium on glutathione levels. The heritability of glutathione content was 91%. The application of cadmium significantly reduced the mean level of GSH. However, this reduction in GSH was not due to additive genetic influences in our sample. |
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| DATE PUBLISHED |
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| HISTORY |
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| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
2006/04/14 09:00 |
| medline |
2006/05/12 09:00 |
| entrez |
2006/04/14 09:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Shekar SN |
|
Shekar |
Sri Niranjan |
SN |
|
Genetic Epidemiology Unit, Queensland Institute of Medical Research, Brisbane, Queensland, Australia. sri.shekar@qimr.edu.au |
| Banerjee T |
|
Banerjee |
Tathagata |
T |
|
|
| Biswas A |
|
Biswas |
Atanu |
A |
|
|
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| INVESTIGATORS |
|
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| JOURNAL |
|
| VOLUME: 9 |
| ISSUE: 1 |
| TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies |
| ISOABBREVIATION: Twin Res Hum Genet |
| YEAR: 2006 |
| MONTH: Feb |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 1832-4274 |
| ISSNTYPE: Print |
|
| MEDLINE JOURNAL |
|
| MEDLINETA: Twin Res Hum Genet |
| COUNTRY: England |
| ISSNLINKING: 1832-4274 |
| NLMUNIQUEID: 101244624 |
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| PUBLICATION TYPE |
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| PUBLICATIONTYPE TEXT |
| Journal Article |
| Twin Study |
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| COMMENTS AND CORRECTIONS |
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| GRANTS |
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| GENERAL NOTE |
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| KEYWORDS |
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| MESH HEADINGS |
|
| DESCRIPTORNAME |
QUALIFIERNAME |
| Adolescent |
|
| Adult |
|
| Cadmium |
pharmacology |
| Chi-Square Distribution |
pharmacology |
| Erythrocytes |
metabolism |
| Glutathione |
metabolism |
| Humans |
metabolism |
| Likelihood Functions |
metabolism |
| Male |
metabolism |
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| SUPPLEMENTARY MESH |
|
|
| GENE SYMBOLS |
|
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| CHEMICALS |
|
| REGISTRYNUMBER |
NAMEOFSUBSTANCE |
| 00BH33GNGH |
Cadmium |
| GAN16C9B8O |
Glutathione |
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| OTHER ID's |
|
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|
