Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
16354502
TITLE
Multivariate genetic analysis of academic skills of the Queensland core skills test and IQ highlight the importance of genetic g.
ABSTRACT
This study examined the genetic and environmental relationships among 5 academic achievement skills of a standardized test of academic achievement, the Queensland Core Skills Test (QCST; Queensland Studies Authority, 2003a). QCST participants included 182 monozygotic pairs and 208 dizygotic pairs (mean 17 years +/- 0.4 standard deviation). IQ data were included in the analysis to correct for ascertainment bias. A genetic general factor explained virtually all genetic variance in the component academic skills scores, and accounted for 32% to 73% of their phenotypic variances. It also explained 56% and 42% of variation in Verbal IQ and Performance IQ respectively, suggesting that this factor is genetic g. Modest specific genetic effects were evident for achievement in mathematical problem solving and written expression. A single common factor adequately explained common environmental effects, which were also modest, and possibly due to assortative mating. The results suggest that general academic ability, derived from genetic influences and to a lesser extent common environmental influences, is the primary source of variation in component skills of the QCST.
DATE PUBLISHED
2005 Dec
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2005/12/16 09:00
medline 2006/03/15 09:00
entrez 2005/12/16 09:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Wainwright MA Wainwright Mark A MA Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Brisbane, QLD, Australia. Mark.Wainwright@qimr.edu.au
Wright MJ Wright Margaret J MJ
Luciano M Luciano Michelle M
Geffen GM Geffen Gina M GM
Martin NG Martin Nicholas G NG
INVESTIGATORS
JOURNAL
VOLUME: 8
ISSUE: 6
TITLE: Twin research and human genetics : the official journal of the International Society for Twin Studies
ISOABBREVIATION: Twin Res Hum Genet
YEAR: 2005
MONTH: Dec
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 1832-4274
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Twin Res Hum Genet
COUNTRY: England
ISSNLINKING: 1832-4274
NLMUNIQUEID: 101244624
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Analysis of Variance
Female
Humans
Intelligence Tests
Male
Multivariate Analysis
Problem Solving physiology
Queensland physiology
Twins, Dizygotic genetics
Twins, Monozygotic genetics
Writing genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's