Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
14511436
TITLE
Accuracy of mothers' retrospective reports of smoking during pregnancy: comparison with twin sister informant ratings.
ABSTRACT
Retrospective assessment of maternal smoking or substance use during pregnancy is sometimes unavoidable. The unusually close relationship of twin sister pairs permits comparison of self-report data versus co-twin informant data on substance use during pregnancy. Information about smoking during pregnancy has been gathered from a series of mothers from an Australian volunteer twin panel (576 women reporting on 995 pregnancies), supplemented in many cases by independent ratings of their smoking by twin sister informants (821 pregnancies). Estimates of the proportion of women who had never smoked regularly (56-58%), who had smoked but did not smoke during a particular pregnancy (16-21%), or who smoked throughout the pregnancy (16-18%), were in good agreement whether based on self-report or twin sister informant data. However, informants underreported cases who smoked during the first trimester but then quit (1-3% versus 7-9% by self-report). Women who smoked throughout pregnancy (by informant report) rarely denied a history of regular smoking (< 1%), although a small proportion of apparent false negative cases were identified where they either denied smoking during a pregnancy (9%) or denied smoking beyond the first trimester (10%). We conclude that retrospective smoking data can safely be used to identify potential associations of later child outcomes with maternal smoking during pregnancy.
DATE PUBLISHED
2003 Aug
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2003/09/27 05:00
medline 2005/02/03 09:00
entrez 2003/09/27 05:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Heath AC Heath Andrew C AC Missouri Alcoholism Research Center, Department of Psychiatry,Washington University School of Medicine, St Louis, Missouri, USA. andrew@matlock.wustl.edu
Knopik VS Knopik Valerie S VS
Madden PA Madden Pamela A PA
Neuman RJ Neuman Rosalind J RJ
Lynskey MJ Lynskey Michael J MJ
Slutske WS Slutske Wendy S WS
Jacob T Jacob Theodore T
Martin NG Martin Nicholas G NG
INVESTIGATORS
JOURNAL
VOLUME: 6
ISSUE: 4
TITLE: Twin research : the official journal of the International Society for Twin Studies
ISOABBREVIATION: Twin Res
YEAR: 2003
MONTH: Aug
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 1369-0523
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Twin Res
COUNTRY: Australia
ISSNLINKING: 1369-0523
NLMUNIQUEID: 9815819
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Evaluation Studies
Journal Article
Research Support, U.S. Gov't, P.H.S.
Twin Study
COMMENTS AND CORRECTIONS
GRANTS
GRANTID AGENCY COUNTRY
AA07728 NIAAA NIH HHS United States
AA11998 NIAAA NIH HHS United States
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Cohort Studies
Disclosure
Female
Humans
Pregnancy
Pregnancy Complications epidemiology
Questionnaires epidemiology
Reproducibility of Results epidemiology
Retrospective Studies epidemiology
Smoking epidemiology
Twins epidemiology
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's