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| PMID |
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| TITLE |
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| Special twin environments, genetic influences and their effects on the handedness of twins and their siblings. |
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| ABSTRACT |
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| It has been suggested that twinning may influence handedness through the effects of birth order, intra-uterine crowding and mirror imaging. The influence of these effects on handedness (for writing and throwing) was examined in 3657 Monozygotic (MZ) and 3762 Dizygotic (DZ) twin pairs (born 1893-1992). Maximum likelihood analyses revealed no effects of birth order on the incidence of left-handedness. Twins were no more likely to be left-handed than their singleton siblings (n = 1757), and there were no differences between the DZ co-twin and sibling-twin covariances, suggesting that neither intra-uterine crowding nor the experience of being a twin affects handedness. There was no evidence of mirror imaging; the co-twin correlations of monochorionic and dichorionic MZ twins did not differ. Univariate genetic analyses revealed common environmental factors to be the most parsimonious explanation of familial aggregation for the writing-hand measure, while additive genetic influences provided a better interpretation of the throwing hand data. |
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| DATE PUBLISHED |
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| HISTORY |
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| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
2003/05/02 05:00 |
| medline |
2003/08/06 05:00 |
| entrez |
2003/05/02 05:00 |
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| AUTHORS |
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| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Medland SE |
|
Medland |
Sarah E |
SE |
|
Genetic Epidemiology Unit, Queensland Institute of Medical Research, 300 Herston Road, Brisbane, Queensland 4029, Australia. sarahMe@qimr.edu.au |
| Wright MJ |
|
Wright |
Margaret J |
MJ |
|
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| Geffen GM |
|
Geffen |
Gina M |
GM |
|
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| Hay DA |
|
Hay |
David A |
DA |
|
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| Levy F |
|
Levy |
Florence |
F |
|
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| Martin NG |
|
Martin |
Nicholas G |
NG |
|
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| Duffy DL |
|
Duffy |
David L |
DL |
|
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| INVESTIGATORS |
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| JOURNAL |
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| VOLUME: 6 |
| ISSUE: 2 |
| TITLE: Twin research : the official journal of the International Society for Twin Studies |
| ISOABBREVIATION: Twin Res |
| YEAR: 2003 |
| MONTH: Apr |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 1369-0523 |
| ISSNTYPE: Print |
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| MEDLINE JOURNAL |
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| MEDLINETA: Twin Res |
| COUNTRY: Australia |
| ISSNLINKING: 1369-0523 |
| NLMUNIQUEID: 9815819 |
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| PUBLICATION TYPE |
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| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
| Research Support, U.S. Gov't, P.H.S. |
| Twin Study |
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| COMMENTS AND CORRECTIONS |
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| GRANTS |
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| GENERAL NOTE |
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| KEYWORDS |
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| MESH HEADINGS |
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| DESCRIPTORNAME |
QUALIFIERNAME |
| Birth Order |
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| Chi-Square Distribution |
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| Female |
|
| Functional Laterality |
genetics |
| Humans |
genetics |
| Likelihood Functions |
genetics |
| Male |
genetics |
| Placenta |
genetics |
| Pregnancy |
genetics |
| Siblings |
genetics |
| Social Environment |
genetics |
| Twins |
genetics |
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| SUPPLEMENTARY MESH |
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| GENE SYMBOLS |
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| CHEMICALS |
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| OTHER ID's |
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