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| PMID |
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| TITLE |
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| Genetic sources of covariation among P3(00) and online performance variables in a delayed-response working memory task. |
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| ABSTRACT |
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| Genetic and environmental sources of covariation among the P3(00) and online performance elicited in a delayed-response working memory task, and psychometric IQ assessed by the multidimensional aptitude battery, were examined in an adolescent twin sample. An association between frontal P3 latency and task performance (phenotypic r=-0.33; genotypic r=-0.49) was indicated, with genes (i.e. twin status) accounting for a large part of the covariation (>70%). In contrast, genes influencing P3 amplitude mediated only a small part (2%) of the total genetic variation in task performance. While task performance mediated 15% of the total genetic variation in IQ (phenotypic r=0.22; genotypic r=0.39) there was no association between P3 latency and IQ or P3 amplitude with IQ. The findings provide some insight into the inter-relationships among psychophysiological, performance and psychometric measures of cognitive ability, and provide support for a levels-of-processing genetic model of cognition where genes act on specific sub-components of cognitive processes. |
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| DATE PUBLISHED |
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| HISTORY |
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| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
2002/10/19 04:00 |
| medline |
2003/03/28 05:00 |
| entrez |
2002/10/19 04:00 |
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| AUTHORS |
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| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Wright MJ |
|
Wright |
Margaret J |
MJ |
|
Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, PO Royal Brisbane Hospital, Brisbane, Queensland 4029, Australia. margiew@qimr.edu.au |
| Luciano M |
|
Luciano |
Michelle |
M |
|
|
| Hansell NK |
|
Hansell |
Narelle K |
NK |
|
|
| Geffen GM |
|
Geffen |
Gina M |
GM |
|
|
| Geffen LB |
|
Geffen |
Laurie B |
LB |
|
|
| Martin NG |
|
Martin |
Nicholas G |
NG |
|
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| INVESTIGATORS |
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| JOURNAL |
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| VOLUME: 61 |
| ISSUE: 1-2 |
| TITLE: Biological psychology |
| ISOABBREVIATION: Biol Psychol |
| YEAR: 2002 |
| MONTH: Oct |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 0301-0511 |
| ISSNTYPE: Print |
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| MEDLINE JOURNAL |
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| MEDLINETA: Biol Psychol |
| COUNTRY: Netherlands |
| ISSNLINKING: 0301-0511 |
| NLMUNIQUEID: 0375566 |
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| PUBLICATION TYPE |
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| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
| Research Support, U.S. Gov't, Non-P.H.S. |
| Twin Study |
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| COMMENTS AND CORRECTIONS |
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| GRANTS |
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| GENERAL NOTE |
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| KEYWORDS |
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| MESH HEADINGS |
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| DESCRIPTORNAME |
QUALIFIERNAME |
| Adolescent |
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| Adult |
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| Analysis of Variance |
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| Aptitude Tests |
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| Arousal |
physiology |
| Cerebral Cortex |
physiology |
| Event-Related Potentials, P300 |
genetics |
| Female |
genetics |
| Genotype |
genetics |
| Humans |
genetics |
| Individuality |
genetics |
| Intelligence |
genetics |
| Male |
genetics |
| Mental Recall |
physiology |
| Orientation |
physiology |
| Pattern Recognition, Visual |
physiology |
| Phenotype |
physiology |
| Psychomotor Performance |
physiology |
| Reaction Time |
genetics |
| Twins, Dizygotic |
genetics |
| Twins, Monozygotic |
genetics |
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| SUPPLEMENTARY MESH |
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| GENE SYMBOLS |
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| CHEMICALS |
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| OTHER ID's |
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