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Psychiatric Genetics and Statistical Genetics
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Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID

11964723

TITLE

Applying statistical approaches in the dissection of genes versus environment for asthma and allergic disease.

ABSTRACT

Now that some of the genes involved in asthma and allergy have been identified, interest is turning to how genetic predisposition interacts with exposure to environmental risk factors. These questions are best answered by studies in which both genotypes and other risk factors are measured, but even simpler studies, in which family history is used as a proxy for genotype, have made suggestive findings. For example, early breast feeding may increase the risk of allergic disease in genetically susceptible children, and decrease the risk of 'sporadic' allergy. This review also addresses the overall importance of genetic causes of allergic disease in the general population.

DATE PUBLISHED

2001 Oct

HISTORY

PUBSTATUS	PUBSTATUSDATE
pubmed	2002/04/20 10:00
medline	2002/06/14 10:01
entrez	2002/04/20 10:00

AUTHORS

NAME	COLLECTIVENAME	LASTNAME	FORENAME	INITIALS	AFFILIATION	AFFILIATIONINFO
Duffy DL		Duffy	D L	DL		Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia. davidd@qimr.edu.au

INVESTIGATORS

JOURNAL

VOLUME: 1

ISSUE: 5

TITLE: Current opinion in allergy and clinical immunology

ISOABBREVIATION: Curr Opin Allergy Clin Immunol

YEAR: 2001

MONTH: Oct

DAY:

MEDLINEDATE:

SEASON:

CITEDMEDIUM: Print

ISSN: 1528-4050

ISSNTYPE: Print

MEDLINE JOURNAL

MEDLINETA: Curr Opin Allergy Clin Immunol

COUNTRY: United States

ISSNLINKING: 1473-6322

NLMUNIQUEID: 100936359

PUBLICATION TYPE

PUBLICATIONTYPE TEXT

Journal Article

Review

COMMENTS AND CORRECTIONS

GRANTS

GENERAL NOTE

KEYWORDS

MESH HEADINGS

DESCRIPTORNAME	QUALIFIERNAME
Asthma	genetics
Data Interpretation, Statistical	genetics
Environment	genetics
Genetic Linkage	genetics
Humans	genetics
Hypersensitivity, Immediate	genetics
Quantitative Trait, Heritable	genetics
Risk Factors	genetics

SUPPLEMENTARY MESH

GENE SYMBOLS

CHEMICALS

OTHER ID's