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PMID |
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TITLE |
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Applying statistical approaches in the dissection of genes versus environment for asthma and allergic disease. |
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ABSTRACT |
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Now that some of the genes involved in asthma and allergy have been identified, interest is turning to how genetic predisposition interacts with exposure to environmental risk factors. These questions are best answered by studies in which both genotypes and other risk factors are measured, but even simpler studies, in which family history is used as a proxy for genotype, have made suggestive findings. For example, early breast feeding may increase the risk of allergic disease in genetically susceptible children, and decrease the risk of 'sporadic' allergy. This review also addresses the overall importance of genetic causes of allergic disease in the general population. |
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DATE PUBLISHED |
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HISTORY |
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PUBSTATUS |
PUBSTATUSDATE |
pubmed |
2002/04/20 10:00 |
medline |
2002/06/14 10:01 |
entrez |
2002/04/20 10:00 |
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AUTHORS |
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NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Duffy DL |
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Duffy |
D L |
DL |
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Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia. davidd@qimr.edu.au |
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INVESTIGATORS |
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JOURNAL |
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VOLUME: 1 |
ISSUE: 5 |
TITLE: Current opinion in allergy and clinical immunology |
ISOABBREVIATION: Curr Opin Allergy Clin Immunol |
YEAR: 2001 |
MONTH: Oct |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Print |
ISSN: 1528-4050 |
ISSNTYPE: Print |
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MEDLINE JOURNAL |
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MEDLINETA: Curr Opin Allergy Clin Immunol |
COUNTRY: United States |
ISSNLINKING: 1473-6322 |
NLMUNIQUEID: 100936359 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Journal Article |
Review |
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COMMENTS AND CORRECTIONS |
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GRANTS |
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GENERAL NOTE |
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KEYWORDS |
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MESH HEADINGS |
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DESCRIPTORNAME |
QUALIFIERNAME |
Asthma |
genetics |
Data Interpretation, Statistical |
genetics |
Environment |
genetics |
Genetic Linkage |
genetics |
Humans |
genetics |
Hypersensitivity, Immediate |
genetics |
Quantitative Trait, Heritable |
genetics |
Risk Factors |
genetics |
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SUPPLEMENTARY MESH |
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GENE SYMBOLS |
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CHEMICALS |
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OTHER ID's |
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