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PMID |
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TITLE |
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Genetic influence on ERP slow wave measures of working memory. |
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ABSTRACT |
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Individual differences in the variance of event-related potential (ERP) slow wave (SW) measures were examined. SW was recorded at prefrontal and parietal sites during memory and sensory trials of a delayed-response task in 391 adolescent twin pairs. Familial resemblance was identified and there was a strong suggestion of genetic influence. A common genetic factor influencing memory and sensory SW was identified at the prefrontal site (accounting for an estimated 35%-37% of the reliable variance) and at the parietal site (51%-52% of the reliable variance). Remaining reliable variance was influenced by unique environmental factors. Measurement error accounted for 24% to 30% of the total variance of each variable. The results show genetic independence for recording site, but not trial type, and suggest that the genetic factors identified relate more directly to brain structures, as defined by the cognitive functions they support, than to the cognitive networks that link them. |
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DATE PUBLISHED |
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HISTORY |
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PUBSTATUS |
PUBSTATUSDATE |
pubmed |
2002/02/13 10:00 |
medline |
2002/04/17 10:01 |
entrez |
2002/02/13 10:00 |
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AUTHORS |
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NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
Hansell NK |
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Hansell |
N K |
NK |
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Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Royal Brisbane Hospital, Australia. narelleH@qimr.edu.au |
Wright MJ |
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Wright |
M J |
MJ |
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Geffen GM |
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Geffen |
G M |
GM |
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Geffen LB |
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Geffen |
L B |
LB |
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Smith GA |
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Smith |
G A |
GA |
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Martin NG |
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Martin |
N G |
NG |
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INVESTIGATORS |
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JOURNAL |
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VOLUME: 31 |
ISSUE: 6 |
TITLE: Behavior genetics |
ISOABBREVIATION: Behav. Genet. |
YEAR: 2001 |
MONTH: Nov |
DAY: |
MEDLINEDATE: |
SEASON: |
CITEDMEDIUM: Print |
ISSN: 0001-8244 |
ISSNTYPE: Print |
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MEDLINE JOURNAL |
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MEDLINETA: Behav Genet |
COUNTRY: United States |
ISSNLINKING: 0001-8244 |
NLMUNIQUEID: 0251711 |
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PUBLICATION TYPE |
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PUBLICATIONTYPE TEXT |
Journal Article |
Research Support, Non-U.S. Gov't |
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COMMENTS AND CORRECTIONS |
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GRANTS |
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GENERAL NOTE |
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KEYWORDS |
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MESH HEADINGS |
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DESCRIPTORNAME |
QUALIFIERNAME |
Adolescent |
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Cerebral Cortex |
physiology |
Electroencephalography |
physiology |
Female |
physiology |
Genetic Variation |
physiology |
Humans |
physiology |
Individuality |
physiology |
Intelligence |
genetics |
Male |
genetics |
Models, Genetic |
genetics |
Parietal Lobe |
physiology |
Prefrontal Cortex |
physiology |
Retention (Psychology) |
physiology |
Social Environment |
physiology |
Twins |
genetics |
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SUPPLEMENTARY MESH |
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GENE SYMBOLS |
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CHEMICALS |
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OTHER ID's |
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