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| PMID |
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| TITLE |
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| Genetic covariance among measures of information processing speed, working memory, and IQ. |
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| ABSTRACT |
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| The genetic relationship between lower (information processing speed), intermediate (working memory), and higher levels (complex cognitive processes as indexed by IQ) of mental ability was studied in a classical twin design comprising 166 monozygotic and 190 dizygotic twin pairs. Processing speed was measured by a choice reaction time (RT) task (2-, 4-, and 8-choice), working memory by a visual-spatial delayed response task, and IQ by the Multidimensional Aptitude Battery. Multivariate analysis, adjusted for test-retest reliability, showed the presence of a genetic factor influencing all variables and a genetic factor influencing 4- and 8-choice RTs, working memory, and IQ. There were also genetic factors specific to 8-choice RT, working memory, and IQ. The results confirmed a strong relationship between choice RT and IQ (phenotypic correlations: -0.31 to -0.53 in females, -0.32 to -0.56 in males; genotypic correlations: -0.45 to -0.70) and a weaker but significant association between working memory and IQ (phenotypic: 0.26 in females, 0.13 in males; genotypic: 0.34). A significant part of the genetic variance (43%) in IQ was not related to either choice RT or delayed response performance, and may represent higher order cognitive processes. |
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| DATE PUBLISHED |
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| HISTORY |
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| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
2002/02/13 10:00 |
| medline |
2002/04/17 10:01 |
| entrez |
2002/02/13 10:00 |
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| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Luciano M |
|
Luciano |
M |
M |
|
Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia. michelLu@qimr.edu.au |
| Wright M |
|
Wright |
M |
M |
|
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| Smith GA |
|
Smith |
G A |
GA |
|
|
| Geffen GM |
|
Geffen |
G M |
GM |
|
|
| Geffen LB |
|
Geffen |
L B |
LB |
|
|
| Martin NG |
|
Martin |
N G |
NG |
|
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| INVESTIGATORS |
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| JOURNAL |
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| VOLUME: 31 |
| ISSUE: 6 |
| TITLE: Behavior genetics |
| ISOABBREVIATION: Behav. Genet. |
| YEAR: 2001 |
| MONTH: Nov |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 0001-8244 |
| ISSNTYPE: Print |
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| MEDLINE JOURNAL |
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| MEDLINETA: Behav Genet |
| COUNTRY: United States |
| ISSNLINKING: 0001-8244 |
| NLMUNIQUEID: 0251711 |
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| PUBLICATION TYPE |
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| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
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| COMMENTS AND CORRECTIONS |
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| GRANTS |
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| GENERAL NOTE |
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| KEYWORDS |
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| MESH HEADINGS |
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| DESCRIPTORNAME |
QUALIFIERNAME |
| Adolescent |
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| Cerebral Cortex |
physiology |
| Female |
physiology |
| Humans |
physiology |
| Intelligence |
genetics |
| Male |
genetics |
| Memory, Short-Term |
physiology |
| Models, Genetic |
physiology |
| Multivariate Analysis |
physiology |
| Phenotype |
physiology |
| Reaction Time |
genetics |
| Twins |
genetics |
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| SUPPLEMENTARY MESH |
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| GENE SYMBOLS |
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| CHEMICALS |
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| OTHER ID's |
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