Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
11665306
TITLE
The influence of genetic and environmental factors in estimations of current body size, desired body size, and body dissatisfaction.
ABSTRACT
The objective was to investigate the genetic epidemiology of figural stimuli. Standard figural stimuli were available from 5,325 complete twin pairs: 1,751 (32.9%) were monozygotic females, 1,068 (20.1%) were dizygotic females, 752 (14.1%) were monozygotic males, 495 (9.3%) were dizygotic males, and 1,259 (23.6%) were dizygotic male-female pairs. Univariate twin analyses were used to examine the influences on the individual variation in current body size and ideal body size. These data were analysed separately for men and women in each of five age groups. A factorial analysis of variance, with polychoric correlations between twin pairs as the dependent variable, and age, sex, zygosity, and the three interaction terms (age x sex, age x zygosity, sex x zygosity) as independent variables, was used to examine trends across the whole data set. Results showed genetic influences had the largest impact on the individual variation in current body size measures, whereas non-shared environmental influences were associated with the majority of individual variation in ideal body size. There was a significant main effect of zygosity (heritability) in predicting polychoric correlations for current body size and body dissatisfaction. There was a significant main effect of gender and zygosity in predicting ideal body size, with a gender x zygosity interaction. In common with BMI, heritability is important in influencing the estimation of current body size. Selection of desired body size for both men and women is more strongly influenced by environmental factors.
DATE PUBLISHED
2001 Aug
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2001/10/23 10:00
medline 2002/01/05 10:01
entrez 2001/10/23 10:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Wade TD Wade T D TD School of Psychology, Flinders University of South Australia, PO Box 2100, Adelaide, SA, 5001, Australia. tracey.wade@flinders.edu.au
Bulik CM Bulik C M CM
Heath AC Heath A C AC
Martin NG Martin N G NG
Eaves LJ Eaves L J LJ
INVESTIGATORS
JOURNAL
VOLUME: 4
ISSUE: 4
TITLE: Twin research : the official journal of the International Society for Twin Studies
ISOABBREVIATION: Twin Res
YEAR: 2001
MONTH: Aug
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 1369-0523
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Twin Res
COUNTRY: Australia
ISSNLINKING: 1369-0523
NLMUNIQUEID: 9815819
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Twin Study
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Age Distribution
Aged
Analysis of Variance
Body Constitution physiology
Body Image physiology
Body Mass Index physiology
Female physiology
Genetics, Behavioral statistics & numerical data
Human Body statistics & numerical data
Humans statistics & numerical data
Male statistics & numerical data
Middle Aged statistics & numerical data
Personal Satisfaction statistics & numerical data
Sex Distribution statistics & numerical data
Social Environment statistics & numerical data
Twins, Dizygotic statistics & numerical data
Twins, Monozygotic statistics & numerical data
Virginia statistics & numerical data
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's