Genetic Epidemiology, Translational Neurogenomics, Psychiatric Genetics and Statistical Genetics Laboratories investigate the pattern of disease in families, particularly identical and non-identical twins, to assess the relative importance of genes and environment in a variety of important health problems.
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PMID
11206089
TITLE
Measurement models for sexual orientation in a community twin sample.
ABSTRACT
Multivariate structural equation modeling techniques have been applied to examine the causes of individual differences in responses to several items concerning sexual orientation. To minimize potential ascertainment and response biases, the study sample involved a large (N = 4901) community-based cohort of Australian twins aged 18-52 who answered an anonymous questionnaire on sexual behavior and attitudes. The statistical power of the analysis was increased by the availability of multiple measures of sexual orientation (behaviors, attitudes and feelings), providing stronger evidence for the existence of additive genetic influences on this phenotype than in a previous analysis (Bailey et al., 2000). Estimates of the heritability of homosexuality in this sample ranged between 50 and 60% in females but were significantly lower (heritability of approximately 30%) in males.
DATE PUBLISHED
2000 Jul
HISTORY
PUBSTATUS PUBSTATUSDATE
pubmed 2001/02/24 12:00
medline 2001/03/10 10:01
entrez 2001/02/24 12:00
AUTHORS
NAME COLLECTIVENAME LASTNAME FORENAME INITIALS AFFILIATION AFFILIATIONINFO
Kirk KM Kirk K M KM Queensland Institute of Medical Research and Joint Genetics Program, The University of Queensland, Brisbane, Australia. kathE@qimr.edu.au
Bailey JM Bailey J M JM
Dunne MP Dunne M P MP
Martin NG Martin N G NG
INVESTIGATORS
JOURNAL
VOLUME: 30
ISSUE: 4
TITLE: Behavior genetics
ISOABBREVIATION: Behav. Genet.
YEAR: 2000
MONTH: Jul
DAY:
MEDLINEDATE:
SEASON:
CITEDMEDIUM: Print
ISSN: 0001-8244
ISSNTYPE: Print
MEDLINE JOURNAL
MEDLINETA: Behav Genet
COUNTRY: United States
ISSNLINKING: 0001-8244
NLMUNIQUEID: 0251711
PUBLICATION TYPE
PUBLICATIONTYPE TEXT
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Twin Study
COMMENTS AND CORRECTIONS
GRANTS
GENERAL NOTE
KEYWORDS
MESH HEADINGS
DESCRIPTORNAME QUALIFIERNAME
Adolescent
Adult
Cohort Studies
Female
Homosexuality genetics
Humans genetics
Male genetics
Middle Aged genetics
Models, Genetic genetics
Phenotype genetics
Sexual Behavior genetics
Social Environment genetics
Twins, Dizygotic genetics
Twins, Monozygotic genetics
SUPPLEMENTARY MESH
GENE SYMBOLS
CHEMICALS
OTHER ID's