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| PMID |
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| TITLE |
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| Effects of lifestyle, personality, symptoms of anxiety and depression, and genetic predisposition on subjective sleep disturbance and sleep pattern. |
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| ABSTRACT |
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| The effects on sleep pattern ('short-sleep' versus 'long-sleep') and subjective sleep disturbance of genotype, personality, symptoms of anxiety and depression, and lifestyle, were examined using survey data on a clinically unselected sample of adult Australian twin pairs, aged 17-88 years. When the effects of genotype, personality and symptoms were ignored, lifestyle variables appeared to account for roughly 4% of the variance in sleep disturbance, and 9% of the variance in sleep pattern. Significant genetic effects on sleep disturbance and sleep pattern were found, which were only partly explained by the effects of personality and symptoms of anxiety and depression. Much of the association between sleep disturbance and lifestyle appeared to be explained by separate effects of personality and symptoms of anxiety and depression on sleep and lifestyle ('genotype-risk-factor correlation'). There was little evidence for genetically determined differences in sensitivity to the lifestyle variables ('genotype x risk-factor interaction'). |
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| DATE PUBLISHED |
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| HISTORY |
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| PUBSTATUS |
PUBSTATUSDATE |
| pubmed |
1999/04/01 |
| medline |
1999/04/01 00:01 |
| entrez |
1999/04/01 00:00 |
|
| AUTHORS |
|
| NAME |
COLLECTIVENAME |
LASTNAME |
FORENAME |
INITIALS |
AFFILIATION |
AFFILIATIONINFO |
| Heath AC |
|
Heath |
A C |
AC |
|
Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA. |
| Eaves LJ |
|
Eaves |
L J |
LJ |
|
|
| Kirk KM |
|
Kirk |
K M |
KM |
|
|
| Martin NG |
|
Martin |
N G |
NG |
|
|
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| INVESTIGATORS |
|
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| JOURNAL |
|
| VOLUME: 1 |
| ISSUE: 4 |
| TITLE: Twin research : the official journal of the International Society for Twin Studies |
| ISOABBREVIATION: Twin Res |
| YEAR: 1998 |
| MONTH: Dec |
| DAY: |
| MEDLINEDATE: |
| SEASON: |
| CITEDMEDIUM: Print |
| ISSN: 1369-0523 |
| ISSNTYPE: Print |
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| MEDLINE JOURNAL |
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| MEDLINETA: Twin Res |
| COUNTRY: Australia |
| ISSNLINKING: 1369-0523 |
| NLMUNIQUEID: 9815819 |
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| PUBLICATION TYPE |
|
| PUBLICATIONTYPE TEXT |
| Journal Article |
| Research Support, Non-U.S. Gov't |
| Research Support, U.S. Gov't, P.H.S. |
| Twin Study |
|
| COMMENTS AND CORRECTIONS |
|
|
| GRANTS |
|
| GRANTID |
AGENCY |
COUNTRY |
| AG04954 |
NIA NIH HHS |
United States |
| GM30250 |
NIGMS NIH HHS |
United States |
| HL28922 |
NHLBI NIH HHS |
United States |
|
| GENERAL NOTE |
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| KEYWORDS |
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| MESH HEADINGS |
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| DESCRIPTORNAME |
QUALIFIERNAME |
| Adolescent |
|
| Adult |
|
| Aged |
|
| Aged, 80 and over |
|
| Anxiety |
physiopathology |
| Depression |
physiopathology |
| Diseases in Twins |
physiopathology |
| Female |
physiopathology |
| Genetic Predisposition to Disease |
physiopathology |
| Genotype |
physiopathology |
| Humans |
physiopathology |
| Life Style |
physiopathology |
| Male |
physiopathology |
| Middle Aged |
physiopathology |
| Multivariate Analysis |
physiopathology |
| Personality |
physiopathology |
| Questionnaires |
physiopathology |
| Risk Factors |
physiopathology |
| Sex Factors |
physiopathology |
| Sleep |
physiology |
| Sleep Disorders |
genetics |
| Sleep Initiation and Maintenance Disorders |
genetics |
| Time Factors |
genetics |
| Twins, Dizygotic |
genetics |
| Twins, Monozygotic |
genetics |
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| SUPPLEMENTARY MESH |
|
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| GENE SYMBOLS |
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| CHEMICALS |
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| OTHER ID's |
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