# # Seven Acadian pedigrees segregating Ushers syndrome 1c # From Figure 1 of Ayyagari R, Li Y, Smith RJH et al (1995) # Fine Mapping of the Usher Syndrome Type IC to Chromosome 11p14 and # Identification of Flanking Markers by Haplotype Analysis # Mol. Vis. 1:2. # set locus ushers aff . set locus D11S861 mar 28.081 chr11:14448976 set locus D11S419 mar 29.936 chr11:15913066 set locus D11S1397 mar 30.279 chr11:16154142 set locus D11S1890 mar 31.560 chr11:16960872 set locus D11S921 mar 32.067 chr11:17241008 set locus D11S902 mar 32.449 chr11:17445082 # harmonin chr11:17522539-17472018 set locus D11S1888 mar 33.009 chr11:17734511 set locus D11S1310 mar 33.331 chr11:17896608 read pedigree inline 101 1 x x m n 2/3 2/2 1/3 1/2 3/3 3/4 1/4 3/4 101 2 x x f n 1/3 2/2 1/3 2/4 2/3 2/4 2/4 4/4 101 3 1 2 f n 1/2 2/2 3/3 1/4 2/3 2/3 1/2 3/4 101 4 1 2 f n 1/3 2/2 1/3 2/4 2/3 2/4 2/4 4/4 101 5 1 2 f y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 4/4 101 6 1 2 f y x/x x/x x/x x/x x/x x/x x/x x/x 102 4 x x m n 3/4 2/2 1/1 2/2 3/3 2/4 2/4 3/4 102 5 x x f n 2/3 1/2 1/1 2/5 1/3 2/4 1/4 4/4 102 7 4 5 f y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 4/4 102 8 4 5 f n 2/3 1/2 1/1 2/5 1/3 2/4 1/4 4/4 102 9 4 5 f y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 4/4 102 10 4 5 m n 2/4 1/2 1/1 2/5 1/3 2/2 1/2 3/4 102 11 4 5 m y 3/4 2/2 1/1 2/2 3/3 4/4 4/4 4/4 102 12 4 5 m n 2/3 1/2 1/1 2/5 1/3 2/4 1/4 4/4 103 1 x x m n 1/3 2/2 1/1 2/3 1/3 2/4 1/4 2/4 103 2 x x f n 1/3 1/2 1/1 2/3 3/3 1/4 3/4 3/4 103 3 1 2 m n x/x x/x x/x x/x x/x x/x x/x x/x 103 4 1 2 m y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 4/4 103 5 1 2 m n 1/3 1/2 1/1 2/3 3/3 1/4 3/4 3/4 104 1 x x m n 3/5 2/2 1/1 1/2 3/3 3/4 3/4 4/4 104 2 x x f n 1/3 1/2 3/3 2/2 3/3 2/4 2/4 1/4 104 3 1 2 m y 3/3 2/2 1/3 2/2 3/3 4/4 4/4 4/4 104 5 1 2 m n 3/5 2/2 1/3 1/2 3/3 3/4 3/4 4/4 104 6 1 2 m y 3/3 2/2 1/3 2/2 3/3 4/4 4/4 4/4 104 7 1 2 m n 3/5 2/2 1/3 1/2 3/3 3/4 3/4 4/4 104 8 1 2 m n 3/5 2/2 1/3 1/2 3/3 3/4 3/4 1/4 105 1 x x f n 3/4 1/2 1/1 2/2 1/3 3/4 1/4 2/4 105 6 x x m n 1/3 1/2 1/1 2/2 2/3 2/4 1/4 1/2 105 2 6 1 m n 1/4 1/1 1/1 2/2 1/2 2/3 1/1 1/2 105 3 6 1 f n 1/3 1/2 1/1 2/2 2/3 2/4 1/4 1/4 105 4 6 1 f y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 2/4 105 9 6 1 f y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 2/4 105 10 6 1 m y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 2/4 106 1 x x m n 2/3 2/2 1/3 2/2 1/3 3/4 1/4 3/4 106 2 x x f n 3/6 1/2 1/2 2/2 3/3 2/4 2/4 2/4 106 3 1 2 f y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 4/4 106 4 1 2 f n 2/3 2/2 1/3 2/2 1/3 3/4 1/4 3/4 106 5 1 2 m y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 4/4 106 6 1 2 m n 3/6 1/2 1/2 2/2 3/3 2/4 2/4 2/4 107 2 x x f n x/x x/x x/x x/x x/x x/x x/x x/x 107 6 x x m n 1/3 1/2 1/1 2/2 3/3 2/4 2/4 4/5 107 1 6 2 m y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 4/4 107 3 6 2 f n 1/3 1/2 1/1 2/2 3/3 2/4 2/4 4/5 107 5 6 2 f y 3/3 2/2 1/1 2/2 3/3 4/4 4/4 4/4 ;;;; run set ple -2 set loc proband aff edit 101 5 proband to y edit 102 7 proband to y edit 103 4 proband to y edit 104 3 proband to y edit 105 4 proband to y edit 106 3 proband to y edit 107 1 proband to y set ple 0