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Rationale and Scientific Aims of the
Project Twin studies comparing
identical and non identical twins are useful in determining the relative
genetic and environmental contributions to disease. Recent work has shown
glaucoma genes contribute to the development of glaucoma. The extent of this
contribution and the interaction with environmental factors is not clear. We wish to examine around
100 sets of identical twins, 100 sets of non identical twins who are not known
to be affected by glaucoma and approximately 50 sets of twins (both identical
and non identical) who stated that they were affected by glaucoma and their
siblings. The examination will be a
routine glaucoma screen of visual field testing, intraocular pressure
measurement and optic disc photography. This work builds on The
Glaucoma Inheritance Study (GIST) being conducted at the Glaucoma Unit, Royal
Victorian Eye and Researchers Dr Professor Project Staff Interviewers Rebekah Eyers |